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. 2016 Jan 5;35(14):2467–2478. doi: 10.1002/sim.6844

Table 1.

Low‐event‐rate meta‐analyses published in JAMA between 2007 and 2013.

Reference #, multiple analyses .1 and .2 M Endpoint Lead author
13 27 Suicide ideation/attempt Bridge (2007)
14 63 Antibiotic‐associated diarrhea Hempel (2012)
15 15 Risk of low birth weight Kayentao (2013)
16 15 Venous thromboembolism Nalluri (2008)
17.1 8 Lung injury Neto (2012)
17.2 9 Mortality Neto (2012)
18.1 8 Cardiovascular deaths Nguyen (2011)
18.2 11 Prostate cancer‐specific mortality Nguyen (2011)
19.1 21 Incident pancreatitis in 21 large statin trials Preiss (2012)
19.2 7 Incident pancreatitis in 7 large fibrate trials Preiss (2012)
20 16 Fatal adverse events Ranpura (2011)
21 17 All‐cause mortality Rizos (2012)
22.1 17 Major cardiovascular events—inhaled anticholinergics Singh (2008)
22.2 5 Major cardiovascular events—long term Inhaled anticholinergics Singh (2008)
23.1 5 Major cardiovascular events Udell (2013)
23.2 5 Cardiovascular mortality Udell (2013)
24 25 In hospital mortality Wiener (2008)
25 35 Mortality Zarychanski (2013)

Studies where DerSimonian and Laird and Shuster, Guo and Skylar differ substantially are highlighted.

M = number of studies in analysis.