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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Cancer Immunol Res. 2016 Apr 4;4(6):488–497. doi: 10.1158/2326-6066.CIR-15-0297

Figure 1. CD8 T cells required to mediate enriched environment’s reduction in tumor growth.

Figure 1

(A) Experimental design of CD8 T cell depletion experiment. (B) Tumor mass among SE-IgG, SE-CD8, EE-IgG, and EE-CD8 groups at time of sacrifice. (C) Tumor infiltrating CTLs were compared for their surface expression of CD27 proteins. (D) Frequency of tumor infiltrating Tregs. (E) T cell numbers in spleens. (F) Th1 phenotype (CXCR3+CCR4−) of helper T cells. In spleens (G) The frequency of CTLs as a proportion of T cells in the lymph node and spleen. Data are represented as the mean ± SEM; n = 9-10 per group. * P <0.05, ** P < 0.01, *** P < 0.001 The experiment was performed once.