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. Author manuscript; available in PMC: 2016 Dec 1.

Published in final edited form as: J Nucl Med. 2016 Feb 18;57(6):967–973. doi: 10.2967/jnumed.115.171306

TABLE 1.

Paired Label Biodistribution of ¹⁸F-RL-I-5F7 and ¹²⁵I-SGMIB-5F7 in SCID Mice Bearing BT474M1 Xenografts.

Tissue	%Injected Dose/g^a
	1 h		2 h
	¹²⁵I-SGMIB	¹⁸F-RL-I-5F7	¹²⁵I-SGMIB	¹⁸F-RL-I-5F7
Liver	3.27 ± 0.61	3.42 ± 0.57^b	3.12 ± 0.94	3.17 ± 1.13^b
Spleen	2.01 ± 0.62	1.63 ± 0.51	1.85 ± 0.49	1.31± 0.40
Lung	10.47 ± 2.27	9.07 ± 1.06^b	8.03 ± 0.83	6.63 ± 1.46^b
Heart	1.43 ± 0.47	1.30 ± 0.53^b	0.62 ± 0.15	0.54 ± 0.14^b
Kidney	122.68 ± 18.03	139.45 ± 20.54	96.92 ± 30.55	105.02 ± 39.52^b
Stomach	1.91 ± 0.77	1.97 ± 0.78^b	0.59 ± 0.28	0.54 ± 0.23^b
Sm. Intestine	1.71 ± 0.52	2.10 ± 0.59	0.94 ± 0.30	1.28 ± 0.42
Lg. Intestine	1.36 ± 0.31	1.68 ± 0.37	1.89 ± 1.30	2.47 ± 1.63
Muscle	1.16 ± 0.48	1.27 ± 0.50	0.91 ± 0.30	1.10 ± 0.38^b
Blood	1.75 ± 0.84	1.95 ± 0.87	0.65 ± 0.41	0.83 ± 0.43
Bone	0.76 ± 0.37	0.97 ± 0.31	0.78 ± 0.23	1.13 ± 0.28
Brain	0.10 ± 0.04	0.11 ± 0.04	0.07 ± 0.01	0.07 ± 0.02^b
Tumor	26.36 ± 3.12	28.97 ± 3.88	32.52 ± 12.11	36.28 ± 14.10

^a

Mean ± SD (n = 5).

^b

Difference in uptake not statistically significant.