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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Nucl Med. 2016 Feb 18;57(6):967–973. doi: 10.2967/jnumed.115.171306

TABLE 2.

Paired Label Biodistribution of 18F-SFB-5F7 and 125I-SGMIB-5F7 in SCID Mice Bearing BT474M1 Xenografts.

Tissue %Injected Dose/ga
1 h 2 h
125I-SGMIB 18F-SFB 125I-SGMIB 18F-SFB
Liver 2.02 ± 0.47 0.95 ± 0.21 2.18 ± 0.55 0.68 ± 0.13
Spleen 1.08 ± 0.33 0.67 ± 0.37 1.28 ± 0.22 0.52± 0.13
Lung 2.96 ± 0.39 2.31 ± 0.40 2.56 ± 0.70 2.00 ± 0.38b
Heart 0.76 ± 0.20 0.62 ± 0.15 0.62 ± 0.13 0.54 ± 0.15b
Kidney 102.50 ± 26.35 3.90 ± 1.13 93.00 ± 18.82 2.90 ± 0.77
Stomach 1.32 ± 1.17 1.43 ± 1.69b 1.98 ± 1.12 3.21 ± 4.62b
Sm. Intestine 1.17 ± 0.55 0.69 ± 0.33 1.32 ± 0.46 0.59 ± 0.19
Lg. Intestine 1.18 ± 0.47 0.69 ± 0.50 3.86 ± 5.47 1.22 ± 1.66b
Muscle 1.14 ± 0.27 1.16 ± 0.37b 1.21 ± 0.89 1.43 ± 1.20b
Blood 0.96 ± 0.26 1.25 ± 0.29 0.67 ± 0.51 1.44 ± 0.88
Bone 0.88 ± 0.36 0.97 ± 0.55b 0.51 ± 0.09 0.54 ± 0.08b
Brain 0.07 ± 0.02 0.09 ± 0.02 0.08 ± 0.05 0.12 ± 0.06
Tumor 27.88 ± 8.08 23.94 ± 7.00 33.59 ± 6.24 29.59 ± 5.10
a

Mean ± SD (n = 5).

b

Difference in uptake not statistically significant.