Table 1.

Trabecular bone morphometric parameters of the femur and tibia. Kruskal-Wallis (mean±SD, n=4).

Sample	Site	Tissue volume TV mm3	Bone Volume BV mm3	Relative Bone Volume BV/TV%	Trabecular Thickness Tb.Th mm	Trabecular Separation Tb.Sp mm	Trabecular Number Tb.N 1/mm	Structure Model Index SMI	Trabecular Pattern Factor Tb.Pf 1/mm	Bone Mineral Density BMD g/cm3
WT	Femur	1.77 ±0.23	0.17 ±0.081	9.33 ±3.48	0.039 ±0.002	0.21 ±0.061	2.36 ±0.76	1.97 ±0.24	27.17 ±6.64	0.22 ±0.08
Phospho1−/−	Femur	2.17 ±0.32	0.14 ±0.04	6.50 ±0.88	0.035 ±0.002	0.21 ±0.02	1.86 ±0.23	2.13 ±0.05	33.75 ±2.48	0.17 ±0.02
Pit1col2/col2	Femur	a2.57 ±0.28	0.15 ±0.03	5.74 ±0.92	a0.033 ±0.001	0.24 ±0.04	1.72 ±0.25	2.18 ±0.05	35.76 ±1.87	0.14 ±0.02
[Phospho1−/−; Pit1col2/col2]	Femur	c1.56 ±0.44	a,b,c0.05 ±0.03	a,b3.11 ±1.35	a0.033 ±0.003	0.30 ±0.06	a,b,c0.93 ±0.37	a,b2.44 ±0.11	a,b43.81 ±6.90	a,b0.10 ±0.02
K-W p-values	Femur	0.016	0.048	0.018	0.029	0.072	0.023	0.015	0.009	0.015
WT	Tibia	1.10 ±0.25	0.05 ±0.03	4.57 ±1.75	0.029 ±0.003	0.23 ±0.05	1.53 ±0.47	2.18 ±0.10	39.37 ±5.46	0.17 ±0.04
Phospho1−/−	Tibia	1.64 ±0.33	0.07 ±0.02	4.49 ±0.39	0.029 ±0.001	0.22 ±0.01	1.56 ±0.13	2.15 ±0.05	39.63 ±2.13	0.16 ±0.01
Pit1col2/col2	Tibia	a1.87 ±0.39	0.07 ±0.02	3.52 ±0.62	0.028 ±0.001	0.26 ±0.03	1.24 ±0.20	2.23 ±0.09	41.52 ±2.83	0.12 ±0.01
[Phospho1−/−; Pit1col2/col2]	Tibia	b,c1.09 ±0.29	0.04 ±0.01	3.30 ±0.41	0.03 ±0.004	0.26 ±0.01	1.10 ±0.10	b2.34 ±0.10	43.31 ±1.8	a,b0.11 ±0.00
K-W p-values	Tibia	0.024	0.089	0.20	0.94	0.12	0.10	0.076	0.334	0.017

Differences at p<0.05 are indicated by

^avs WT,

^bvs Phospho1−/−,

^cvs P_it1^col2/col2