Table 2.

Cortical bone morphometric parameters of the femur and tibia Kruskal-Wallis (mean±SD, n=4).

Sample	Site	Cross-sectional Tissue Area T.Ar mm2	Cross-sectional Bone Area B.Ar mm2	Relative Bone Area B.Ar/T.Ar %	Cross-sectional Thickness Cs.Th mm	Tissue Mineral Density TMD g/cm3
WT	Femur	1.50 ±0.19	0.65 ±0.18	42.95 ±6.74	0.16 ±0.03	0.89 ±0.03
Phospho1−/−	Femur	a1.82 ±0.13	0.73 ±0.08	40.19 ±3.99	0.15 ±0.02	0.87 ±0.05
Pit1col2/col2	Femur	1.67 ±0.07	0.65 ±0.07	38.97 ±2.89	0.14 ±0.01	0.90 ±0.01
[Phospho1−/−; Pit1col2/col2]	Femur	b1.53 ±0.17	0.48 ±0.11	a,b,c30.84 ±4.57	a,b,c0.11 ±0.02	a,c0.85 ±0.02
K-W p-values	Femur	0.041	0.079	0.029	0.027	0.049
WT	Tibia	1.50 ±0.26	0.64 ±0.21	42.04 ±7.72	0.16 ±0.03	1.01 ±0.06
Phospho1−/−	Tibia	1.61 ±0.17	0.67 ±0.09	41.60 ±3.37	0.15 ±0.02	a0.92 ±0.03
Pit1col2/col2	Tibia	1.70 ±0.11	0.61 ±0.07	35.82 ±1.82	0.13 ±0.01	0.93 ±0.01
[Phospho1−/−; Pit1col2/col2]	Tibia	1.45 ±0.22	0.51 ±0.12	34.67 ±3.61	0.12 ±0.01	a,c0.87 ±0.03
K-W p-values	Tibia	0.434	0.270	0.117	0.106	0.020

Differences at p<0.05 are indicated by

^avs WT,

^bvs Phospho1−/−,

^cvs P_it1^col2/col2