Figure 8.
Template for the 136 OASIS subjects at t0 and log-Jacobian maps (1 year evolution) of the patients with Alzheimer's disease and the healthy control group. The main expansion region concerns the lateral ventricles where the Alzheimer's patients exhibit higher values when compared to the healthy subjects. Moreover, for the patients with Alzheimer's disease we can see an expansion in the temporal horn of the lateral ventricles that does not exist in the non-demented control group. Finally, the atrophy is higher for the Alzheimer's patients and mainly located in several parts of the white matter, in the thalamus and in the hippocampi whereas there is no visible contraction in the thalamus or the hippocampi for the healthy group.