Fig. 2.

Effects of Dietary Galactose on Glycosylation. High resolution mass spectrometry showing glycan structures of transferrin before (a) and after (b) 2 weeks intake of supplementary galactose and corresponding patterns of transferrin isoelectric focusing (IEF). The protein backbone is symbolized by a brown horizontal line. The unoccupied positions are indicated by open arrows () and define the CDG-I-component of this phenotype. The yellow arrow () demonstrates the absence of galactose on one of the truncated glycans, which define the CDG type-II component. The number of sialic acids is indicated above each structure, and the insets at the right show respective IEF results