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. 2016 Apr 21;20:342–370. doi: 10.1007/s10157-015-1216-x

Table 6.

Examination findings of secondary nephrotic syndrome

Examination Measurement items Major findings
Urinalysis Occult blood
Urine Bence Jones protein
Positive in purpura nephritis or vasculitis positive in paraproteinemia
Blood examination Peripheral blood examination Pancytopenia or hemolytic anemia in lupus nephritis
Leukocytosis and thrombocytosis in the cases with infectious diseases ad vasculitis
Biochemical examination Blood sugar markers such as blood glucose, HbA1c, and glycoalbumin in diabetic nephropathy
CRP and inflammatory reactions increase in vasculitis and purpura nephritis
Paraprotein or cryoglobumin is confirmed in in the cases with paraproteinemia
Lipid examination The abnormality of IDL or ApoE is confirmed in lipoprotein glomerulopathy
Immunological examination Anti-nuclear antibody , anti-ds-DNA antibdy, anti-Sm antibody, anti-phosphlipid antibody increase and complements decrease in lupus
nephritis
The positive findings are confirmed in bacterial culture and antigen/antibody detection for pathogenic microbes
Renal biopsy The specific findings are observed in each secondary disease, thus the renal biopsy is useful for the definitive diagnosis of secondary diseases
Imaging test Neoplastic diseases are diagnosed by various imaging tests such as CT, MRI, ultrasonography and bone marrow aspiration
Genetic test Genetic tests are useful in the genetic illnesses