Table 5.

Summary of the potential prognosis miRs in laryngeal cancer

MiRs	Deregulation	Molecular mechanisms	Ref.
miR-101	Downregulation	Low expression of miR-101 was correlated with TNM stage, especially poorer prognosis.	[40]
miR-126	Downregulation	Elevated expression of miR-126 was closely associated with the favorable prognosis of the patients with LSCC.	[56]
miR-152	Downregulation	The expression level of miR-152 was correlated with pT stage and pN stage of supragalottic laryngeal carcinoma.	[57]
miR-19a	Upregulation	The high level of miR-19a was positively correlated with decreased overall survival.	[58]
miR-21/miR-375	Upregulation/Downregulation	High miR-21 or low miR-375 expression in tumor tissues predicted poor prognoses.	[59]
miR-23a	Upregulation	High expression of miR-23a was significantly correlated with patient five-year survival.	[60]
miR-296-5p	Upregulation	The expression of miR-296-5p was substantially related to radioresistance and tumor recurrence in early stage LSCC.	[61]
miR-34c-5p	Downregulation	Low miR-34c-5p expression was significantly associated with worse disease-free and overall survival and an increased risk of recurrence.	[62]