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. 2016 May 15;8(5):1985–1997.

Figure 3.

Figure 3

The effect of siSerpine2 on tumor cells growth. A. Western blot shown that the Serpine2 was elevated in control cells and siCTL transfected cells than siSerpine2 cells. GAPDH was used as a loading control. B. Quantification of Serpine2 mRNA levels in transfected cells. siSerpine2 melanoma cells had significant down-regulation of Serpine2 mRNA compared with that in the control cells (Bars were represented as the mean ± S.E, n=3, **P < 0.01 versus control). C. One solution cell proliferation assay analyzed cell proliferation in SK-MEL-2-siSerpine2 and control cells. Data were from three independent experiments and were average ± S.E. values. **P < 0.01, compared to control cells. D. Serpine2 siRNA did not result in LDH release, indicating Serpine2 siRNA brought little toxic effects on melanoma cells. Data were from three independent experiments and were average ± S.E. values. **P < 0.01, compared to control cells.