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. 2016 May 15;8(5):2127–2137.

Figure 4.

Figure 4

Rescue experiments for miR-124 on DA neurons apoptosis and autophagy. A, B: mRNA and protein levels of ratio of LC3 II/LC3 I in neurons were significantly decreased when miR-124 was rescued in vitro; C, D: Percentage of apoptotic neurons was significantly decreased by miR-124 rescuing in vitro. Compared to the control (6.81%), the percentage of apoptotic cells was increased to 14.8% by MPTP treatment (miR-124 suppression), but declined to 5.28% when miR-124 was rescued (miR-124 mimic transfection) in vitro. **P<0.01, compared to the control (0 μM MPTP).