Figure 5.

Influence of miR-124 expression on AMPK/mTOR pathway associated proteins expression. A: The p-AMPK was increased but p-mTOR was decreased by the suppressed miR-124 in MPTP-treated neurons than the control, the same tendency was observed between the negative and anti-miR-124 group; B: The application of AMPK inhibitor, 1 μM compound C, decreased the p-AMPK level; C: When cells were treated with compound C, the percentage of apoptotic cells was slightly, but not significantly increased. *P<0.05, compared to the control cells (treated with 0 μM MPTP), #P<0.05, compared to the inhibitor control.