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. 2016 May 15;8(5):2127–2137.

Figure 6.

Figure 6

Effects of miR-124 expression on cell apoptosis in in SK-N-SH cells. A: When SK-N-SH cells were treated with 100 μM MPTP, miR-124 expression was significantly deceased compared to that in control cells (0 μM MPTP), but was significantly increased by the miR-124 mimic transfection; B: The percentage of apoptotic SK-N-SH cells was significantly increased by the MPTP treatment (miR-124 suppression) compared with that in control cells (0 μM MPTP), similar results was found in cells treated with the miR-124 inhibitor. However, there was no significant difference for the apoptotic cell percentage between the miR-124 mimic group and the MPTP + miR-124 mimic group; C: The levels for p-AMPK, p-mTOR, AMPK, and mTOR in each were analyzed in each group. The MPTP treatment increased the p-AMPK expression but decreased the p-mTOR level in SK-N-SH cells, similar results were found in the miR-124 inhibitor group. *P<0.05 and **P<0.01, compared to the control cells (0 μM MPTP).