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. 2016 Apr 22;4(6):549–553. doi: 10.1002/ccr3.497

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© 2016 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Histological and immunohistological characterization of thyroid metastasis. (A) H&E of moderately differentiated primary tumor with mucinous features; (B) H&E of metastatic thyroid lesion reveals poorly differentiated colonic adenocarcinoma with desmoplastic features in a background of extracellular mucin; (C) Immunohistochemistry for thyroglobulin (TG) demonstrates staining of the resident thyroid tissue (brown) and no staining of metastatic tumor cells; (D) Immunohistochemistry for thyroid transcription factor‐1 (TTF‐1) demonstrates staining of the resident thyroid tissue (brown) and no staining of metastatic tumor cells.