Table 2. Effects of trimetazidine on parameters of left ventricular structure and systolic function.
| Study group (n=100) | Control group (n=25) | p | |||
|---|---|---|---|---|---|
| Baseline | Third month | Baseline | Third month | ||
| AoD (mm) | 26.3±2.0 | 26.1±2.2 | 25.7±2.1 | 25.9±2.8 | 0.84 |
| LAD (mm) | 37±5 | 37±4 | 38±4 | 38±3 | 0.92 |
| LVEDD (mm) | 49.5±5.0 | 49.7±5.3 | 49.6±4.9 | 49.5±6.0 | 0.78 |
| LVESD (mm) | 31.6±6.1 | 31.4±7.2 | 30.4±5.9 | 30.5±6.2 | 0.64 |
| IVSD (mm) | 10.2±1.6 | 11.1±3.4 | 10.5±1.4 | 10.9±2.6 | 0.58 |
| PWD (mm) | 10.3±1.4 | 10.1±1.2 | 10.4±1.5 | 10.2±1.4 | 0.92 |
| EF (%) | 59±12 | 60±11 | 58±11 | 58±9 | 0.88 |
| LVEDV (cm3) | 91±30 | 95±39 | 93±34 | 94±35 | 0.57 |
| LVESV (cm3) | 39±23 | 39±22 | 40±21 | 41±19 | 0.88 |
| LAV (cm3) | 29±12 | 26±11 | 28±13 | 27±12 | 0.45 |
AoD: aortic root diameter, LAD: left atrial diameter, LVEDD: left ventricular end-diastolic diameter, lVESD: left ventricular end-systolic diameter, IVSD: interventricular septum diastolic dimension, PWD: posterior wall dimension, EF: ejection fraction, LVEDV: left ventricular end-diastolic volume, LVESV: left ventricular end-systolic volume, LAV: left atrial volume