Table 4. Effects of trimetazidine on parameters of left ventricular tissue Doppler echocardiography.
| Study group (n=100) | Control group (n=25) | p | |||
|---|---|---|---|---|---|
| Baseline | Third month | Baseline | Third month | ||
| S' (cm/s) | |||||
| Septal | 7.0±1.9 | 7.5±2.5 | 7.1±1.8 | 7.2±1.2 | 0.04 |
| Lateral | 8.8±2.6 | 8.7±2.7 | 8.5±2.4 | 8.4±2.6 | 0.92 |
| E' (cm/s) | |||||
| Septal | 7.1±2.5 | 7.5±2.3 | 7.2±2.5 | 7.5±2.5 | 0.84 |
| Lateral | 8.7±2.9 | 9.6±2.7 | 8.9±3.0 | 8.8±2.3 | <0.01 |
| A' (cm/s) | |||||
| Septal | 8.8±2.3 | 8.6±2.1 | 8.7±2.5 | 8.7±2.3 | 0.71 |
| Lateral | 11.0±3.2 | 10.0±3.1 | 10.8±3.1 | 10.6±2.9 | 0.19 |
| E/E' | |||||
| Septal | 8.6±6.5 | 8.7±6.4 | 8.5±6.6 | 8.4±6.8 | 0.63 |
| Lateral | 7.5±5.7 | 7.7±6.1 | 7.4±4.9 | 7.5±5.4 | 0.73 |
S’: systolic myocardial velocity, E’: early diastolic myocardial velocity, A’: late diastolic myocardial velocity, E: peak early mitral inflow velocity