Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jun 3;6:27175. doi: 10.1038/srep27175

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

3 × Tg-AD mice were immunized with rCV02 at 3 months (prophylactic; panel A) or 12 months (therapeutic; panels B) of age. The brains were collected for evaluation at 19-months and 21-months of age, respectively. The spectrin content in the soluble fractions of the brain homogenates were detected by Western blot analysis; representative images are shown (lanes 1–3, non-vaccinated control 3 × Tg-AD; lanes 4–6, rCV01-vaccinated 3 × Tg-AD; lanes 6–9, non-vaccinated control C57/BL6). The graphs show the spectrin 150/240 kDa ratio in control and treated mice. Data represent the mean ± SE for each group. Statistically significant differences were determined by ANOVA. **p < 0.01, compared with the control group (3 × Tg-AD).