Table 3.
Adjusted odds ratios (95% confidence intervals) of hospital-acquired complications by GFR and albuminuria categories
| GFR Categories | Persistent Albuminuria Categories | ||
|---|---|---|---|
| Normal to Mildly Increased (<30 mg/g or <3 mg/mmol) | Moderately Increased (30–300 mg/g or 3–30 mg/mmol) | Severely Increased (>300 mg/g or >30 mg/mmol) | |
| HACs | |||
| Normal or high ≥90 ml/min per 1.73 m2 | Reference n=490,816 | 1.25 (1.15–1.35) n=6,195 | 1.33 (1.89–1.48) n=3,188 |
| Mildly decreased: 60–89 ml/min per 1.73 m2 | |||
| Mildly to moderately decreased: 45–59 ml/min per 1.73 m2 | 1.13 (1.08–1.18) n=20,735 | 1.14 (0.93–1.35) n=1,155 | 1.38 (1.14–1.6 n=846 |
| Moderately to severely decreased: 30–44 ml/min per 1.73 m2 | 1.23 (1.16–1.32) n=8,021 | 1.38 (1.11–1.70) n=655 | 1.29 (1.05–1.60) n=726 |
| Severely decreased: 15–29 ml/min per 1.73 m2 | 1.43 (1.29–1.58) n=3,041 | 1.29 (0.95–1.74) n=336 | 1.81 (1.51–2.17) n=835 |
| pHACs | |||
| Normal or high ≥90 ml/min per 1.73 m2 | Reference n=490,816 | 1.21 (1.07–1.36) n=6,195 | 1.36 (1.18–1.58) n=3,188 |
| Mildly decreased: 60–89 ml/min per 1.73 m2 | |||
| Mildly to moderately decreased: 45–59 ml/min per 1.73 m2 | 1.15 (1.05–1.25) n=20,735 | 1.05 (0.84–1.30) n=1,155 | 1.33 (1.05–1.69) n=846 |
| Moderately to severely decreased: 30–44 ml/min per 1.73 m2 | 1.21 (1.09–1.35) n=8,021 | 1.28(0.90–1.84) n=655 | 1.15 (0.88–1.49) n=726 |
| Severely decreased: 15–29 ml/min per 1.73 m2 | 1.41 (1.23–1.62) n=3,041 | 1.36 (1.18–1.58) n=336 | 1.78 (1.43–2.11) n=835 |
CKD was defined by GFR and albuminuria categories according to Kidney Diseae Improving Global Outcomes 2012 guidelines. All odds ratios fully adjusted for age, admission type (elective versus urgent), sex, length of stay, and 17 comorbid conditions, except for reason for admission. Comorbid conditions were cancer, cerebrovascular disease, congestive heart failure, chronic obstructive pulmonary disease, dementia, diabetes with complications, diabetes with no complications, HIV/AIDS, metastatic solid tumor, myocardial infarction, mild liver disease, moderate or severe liver disease, paraplegia or hemiplegia, peptic ulcer disease, peripheral vascular diseases, renal disease, and rheumatologic disease. HAC, hospital-acquired complication; p-HAC, potentially preventable hospital-acquired complication.