Table 4.

Hazard ratios (95% confidence intervals) of all-cause mortality, cardiovascular disease–related mortality, and hospitalization associated with time–varying serum uric acid levels in unadjusted and multivariable–adjusted Cox models

Model	All-Cause Mortality	P Value	CVD Mortality	P Value	CVD Hospitalization	P Value
n (%) of eventsa	87 (43.5)		38 (19.0)		75 (37.5)
Univariate HR (95% CI)	0.91 (0.83 to 1.01)	0.06	0.96 (0.82 to 1.12)	0.57	0.98 (0.86 to 1.10)	0.70
Model 1 (adjustedb) HR (95% CI)	0.83 (0.74 to 0.95)	<0.01	1.01 (0.84 to 1.22)	0.93	0.96 (0.83 to 1.11)	0.62
Model 2 (model 1 and GNRI) HR (95% CI)	0.89 (0.79 to 0.98)	0.02	0.87 (0.72 to 1.07)	0.18	0.99 (0.83 to 1.18)	0.91

CVD, cardiovascular disease; HR, hazard ratio; 95% CI, 95% confidence interval; GNRI, geriatric nutritional risk index.

^aNumbers of events are shown as absolute numbers and percentages.

^bAdjusted for age, sex, diabetes status, dialysis vintage, comorbidity index, Kt/V, diuretic use, and vascular access type.