Table 2.

Median (Interquartile Range) of Serum and Urinary Steroids in STSD Patients and Controls Within the 3 Different Subgroups in STSD Patients (Prepubertal, n = 13; Peripubertal, n = 5; Postpubertal, n = 12) and Healthy Sex- and Age-Matched Controls (Prepubertal, n = 15; Peripubertal, n = 5; Postpubertal, n = 19)

	STSD	Controls	P Value
Serum DHEA (nmol/L)
All	6.0 (3.1, 9.1)	20.0 (13.1, 31.7)	<.0001
Prepubertal	6.6 (2.4, 7.6)	20.1 (14.2, 32.8)	<.0001
Peripubertal	5.7 (4.8, 7.4)	11.3 (8.4, 22.3)	.110
Postpubertal	9.0 (6.8, 14.2)	18.4 (11.1, 29.9)	.004
Serum DHEAS (μmol/L)
All	5.1 (4.1, 7.5)	3.5 (1.4, 9.6)	.373
Prepubertal	4.5 (2.0, 5.0)	1.4 (0.7, 3.0)	.014
Peripubertal	6.2 (4.6, 7.1)	3.5 (3.2, 3.7)	.343
Postpubertal	7.1 (6.2, 9.6)	10.1 (6.6, 13.0)	.227
Serum DHEA to DHEAS ratio
All	0.9 (0.1, 1.4)	4.9 (2.3, 16.9)	<.0001
Prepubertal	0.4 (0.1, 1.0)	15.8 (8.5, 36.9)	<.0001
Peripubertal	0.6 (0.2, 1.03)	3.0 (2.3, 6.5)	.029
Postpubertal	1.2 (0.1, 1.6)	2.6 (1.3, 4.5)	.010
Serum testosterone (nmol/L)
All	4.0 (0.4; 11.0)	10.1 (0.4, 17.6)	.145
Prepubertal	0.4 (0.4, 0.7)	0.4 (0.4, 1.22)	.296
Peripubertal	4.0 (1.5, 6.5)	6.3 (2.2, 11.1)	.685
Postpubertal	11.8 (10.4, 15.6)	19.4 (15.3, 25.0)	.008
Urinary androsterone+etiocholanolone excretion (μg/24 h)
All	604 (231, 3526)	780 (235, 4067)	.588
Prepubertal	237 (177, 415)	247 (96, 413)	.957
Peripubertal	466 (226, 567)	456 (256, 1652)	.111
Postpubertal	4055 (2722, 4779)	4193 (3184, 5461)	.521
Urinary 5αTHF to THF ratio
All	2.3 (1.8; 3.2)	1.2 (1.0; 1.7)	<.0001
Prepubertal	1.9 (1.6; 3.1)	1.1 (0.9; 1.3)	.040
Peripubertal	3.2 (3.2; 3.8)	1.2 (1.0; 1.6)	.016
Postpubertal	2.7 (1.9; 3.4)	1.2 (1.1; 2.2)	.003