Table 3.
Interaction of the FTO SNP (rs11076023) with dietary factors on BMI, obesity, waist circumference and Type 2 diabetes
| SNP * Fat energy percentage | SNP * Protein energy percentage | SNP * Carbohydrate energy percentage | SNP * energy adjusted glycemic load | SNP * energy adjusted glycemic index | SNP * dietary fibre |
|---|---|---|---|---|---|
| Beta coefficients ± standard error (Pinteraction)¥ for interaction on BMI | |||||
| 0.009 ± 0.04 (0.79) | 0.10 ± 0.14 (0.44) | 0.004 ± 0.03 (0.89) | 0.003 ± 0.004 (0.52) | 0.03 ± 0.06 (0.57) | −0.03 ± 0.01 (0.03) |
| Beta coefficients ± standard error (Pinteraction)¥ for interaction on obesity | |||||
| 0.0004 ± 0.01 (0.98) | −0.04 ± 0.06 (0.50) | 0.004 ± 0.01 (0.74) | 0.001 ± 0.002 (0.59) | 0.01 ± 0.03 (0.59) | −0.01 ± 0.007 (0.17) |
| Beta coefficients ± standard error (Pinteraction)¥ for interaction on waist circumference | |||||
| −0.12 ± 0.0.09 (0.18) | −0.32 ± 0.34 (0.34) | 0.11 ± 0.07 (0.12) | 0.02 ± 0.01 (0.04) | 0.25 ± 0.14 (0.08) | −0.12 ± 0.04 (0.0008) |
| Beta coefficients ± standard error (Pinteraction)** for interaction on Type 2 diabetes | |||||
| −0.03 ± 0.02 (0.15) | −0.08 ± 0.07 (0.27) | 0.02 ± 0.01 (0.09) | 0.003 ± 0.002 (0.16) | 0.02 ± 0.03 (0.53) | −0.007 ± 0.007 (0.39) |
¥ P values adjusted for age, gender and type 2 diabetes
**P values adjusted for age, gender and obesity