Figure 1.

Richness and diversity of the T‐cell receptor (TCR) β repertoire in the peripheral blood and cerebrospinal fluid (CSF). TCR β richness (number of unique TCR β clonotypes) was significantly greater in the peripheral blood (PB) than in the CSF for all subjects. The unpaired nonparametric T‐test was applied with p‐value 0.0039 (A). TCR β diversity (number of unique TCR β clonotypes per sample normalized by cell count) was also cumulatively higher in PB compared with CSF. LOO p‐value test ranged 0.0078–0.027 (B). LOO, Leave‐One‐Out.