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. 2016 Apr 20;3(6):422–433. doi: 10.1002/acn3.310

Figure 5.

Figure 5

CDR3 sequence relatedness of T‐cell clonotypes expanded in the peripheral blood. Phylogenetic tree analysis of CDR3 amino acid sequence similarities in T‐cell clonotypes that were differentially expanded against idiopathic intracranial hypertension (IIH) and were shared in PB across all fivemultiple sclerosis (MS) patients (as shown in Fig. 4A, C). Representative CDR3 motif clusters are shown as sequence logos (A). CDR3 amino acid sequence logo from exclusively shared clonotypes across MS patients (n = 204) and IIH controls (n = 158) (B). PB, peripheral blood.