Table 3.

Univariable analysis of factors associated with initiation of postoperative chemotherapy

Variable	Hazard ratio (95 % CI)	p value
Age (<75 vs. ≥75)	0.61 (0.32–1.18)	0.164
Gender (M vs. F)	1.05 (0.71–1.56)	0.791
BMI (<30 vs. ≥30)	1.09 (0.72–1.67)	0.678
ASA (1–2 vs. 3–4)	0.68 (0.41–1.12)	0.144
Number of lesions (solitary vs. multiple)	1.7 (1.16–2.52)	0.007
Size of the largest lesion (≤2.5 vs. >2.5 cm)	0.67 (0.44–1.01)	0.006
Steatohepatitis (no vs. yes)	1.04 (0.62–1.76)	0.865
Synchronous resection (no vs. yes)	0.91 (0.37–2.24)	0.843
CEA (≤100 vs. >100)	1.82 (0.55–6.02)	0.359
Surgical technique (minimally invasive vs. open)	1.77 (1.14–2.46)	0.009
Type of resection (minor vs. major)	0.71 (0.44–1.14)	0.146
Margin (R0 vs. R1)	1.02 (0.55–1.91)	0.938
Postoperative complications (yes vs. no)	0.62 (0.40–0.96)	0.027
EBL (>200 vs. ≤200 ml)	0.49 (0.31–0.77)	0.001
LOS (>4 vs. ≤4 days)	0.56 (0.37–0.83)	0.004

CI confidence interval, BMI body mass index, M male, F female, ASA American Society of Anesthesiologists, CEA carcinoembryonic antigen, EBL estimated blood loss, LOS length of stay