Table 3.
Dietary inflammatory index and mortality due to CHD, stroke, COPD and Alzheimer’s disease and unspecified dementia
| DII | DII quartiles |
|||||
|---|---|---|---|---|---|---|
| Continuous | 1 | 2 | 3 | 4 | p -trend | |
| CHD | ||||||
| Cases | 3381 | 803 | 821 | 862 | 895 | |
| HRa | 1.12 | 1.00 | 1.09 | 1.17 | 1.34 | <0.0001 |
| 95 % CI | 1.07–1.16 | Reference | 0.98–1.20 | 1.06–1.29 | 1.20–1.49 | |
| Adjusted HRRb | 1.07 | 1.00 | 1.04 | 1.07 | 1.17 | 0.001 |
| 95 % CI | 1.03–1.11 | Reference | 0.94–1.15 | 0.97–1.19 | 1.05–1.30 | |
| Stroke | ||||||
| Cases | 1439 | 376 | 375 | 341 | 347 | |
| HRa | 1.04 | 1.00 | 1.06 | 0.98 | 1.11 | 0.21 |
| 95 % CI | 0.98–1.10 | Reference | 0.92–1.22 | 0.84–1.14 | 0.94–1.30 | |
| Adjusted HRb | 1.01 | 1.00 | 1.04 | 0.94 | 1.04 | 0.69 |
| 95 % CI | 0.95–1.08 | Reference | 0.90–1.20 | 0.81–1.09 | 0.88–1.22 | |
| COPD | ||||||
| Cases | 1039 | 201 | 251 | 270 | 317 | |
| HRa | 1.36 | 1.00 | 1.38 | 1.62 | 2.27 | <0.0001 |
| 95 % CI | 1.27–1.46 | Reference | 1.14–1.66 | 1.34–1.96 | 1.86–2.76 | |
| Adjusted HRb | 1.13 | 1.00 | 1.16 | 1.28 | 1.43 | 0.0006 |
| 95 % CI | 1.05–1.21 | Reference | 0.96–1.40 | 1.06–1.55 | 1.18–1.75 | |
| Alzheimer’s disease and unspecified dementia | ||||||
| Cases | 1244 | 330 | 334 | 285 | 295 | |
| HRa | 1.00 | 1.00 | 1.07 | 0.92 | 1.05 | 0.98 |
| 95 % CI | 0.94–1.07 | Reference | 0.92–1.24 | 0.78–1.08 | 0.88–1.25 | |
| Adjusted HRb | 0.99 | 1.00 | 1.06 | 0.91 | 1.03 | 0.73 |
| 95 % CI | 0.93–1.05 | Reference | 0.91–1.24 | 0.77–1.07 | 0.86–1.23 | |
Adjusted for age (continuous) and total energy intake (continuous)
Adjusted for age (continuous), BMI (continuous), smoking status (never, former, current), pack-years of smoking (continuous), HRT use (ever, never), education(<high school, high school graduate, more than high school), prevalent diabetes (yes/no), prevalent hypertension (yes/no), prevalent heart disease (yes/no), prevalent cancer (yes/no), total energy intake (continuous)