Table 3.
Examples of multiplicative relative risks across genetic risk score and personal/lifetime risk/protective factors
| Genetic Risk Score | |||||
|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | Q5 | |
| Referent for personal/lifestyle factors | 1.00 | 1.25 | 1.44 | 1.66 | 2.12 |
| OC use 1-4.99 years | 0.62 | 0.78 | 0.89 | 1.03 | 1.31 |
| OC use 5+ years | 0.40 | 0.50 | 0.58 | 0.66 | 0.85 |
| Parity 1 birth | 0.76 | 0.95 | 1.09 | 1.26 | 1.61 |
| Parity 2+ births | 0.58 | 0.73 | 0.84 | 0.96 | 1.23 |
| Tubal ligation | 0.74 | 0.93 | 1.07 | 1.23 | 1.57 |
| Endometriosis | 1.53 | 1.91 | 2.20 | 2.54 | 3.24 |
| Family history | 2.09 | 2.61 | 3.01 | 3.47 | 4.43 |
Note: The relative risk for various combinations can be obtained by multiplying the relevant cells in the table. For example, to obtain the relative risk for a 5+ OC user in Q1 genetic risk score who also has endometriosis, 0.40*1.53=0.61.