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. Author manuscript; available in PMC: 2016 Jun 3.
Published in final edited form as: Am J Obstet Gynecol. 2014 Dec 31;212(5):653.e1–653.16. doi: 10.1016/j.ajog.2014.12.041

FIGURE 6. Metagenomics of the preterm placental microbiome by maternal weight gain.

FIGURE 6

A, The Kendall correlation of metagenomics RAST server–generated Kyoto Encyclopedia of Genes and Genomes functional profile and genus level bacterial abundance were calculated and plotted. The taxa and pathways shown represent the positive (red) or negative (blue) correlations for preterm women with excess GWG. The red square indicates correlation probability value < .05. B, Among preterm placentas, excess GWG is associated with alterations in metabolic function. Detailed analysis on whole genome shotgun data show that excess GWG has decreased abundance of folate biosynthesis and butanoate metabolism.

GWG, gestational weight gain; LDA, linear discriminate analysis.

Antony. The preterm placental microbiome varies with excess weight gain. Am J Obstet Gynecol 2015.