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Stability of Cu2+-dependent L-S (A) and D-S (B) in 90% FBS for different times, respectively. (C) Denaturing PAGE of the Cu2+-dependent L-DNAzyme in the absence (0) or presence (1) of Cu2+ in the buffer with 0, 10%, 30%, and 50% FBS. (D) Response of L-DNAzyme to different concentrations (0, 0.5, 0.75, 1, 2.5, 5, 10, 20, and 30 μM) of Cu2+ in 10% FBS.
