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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: J Crohns Colitis. 2016 Feb 29;10(9):1087–1095. doi: 10.1093/ecco-jcc/jjw061

Fig. 4. TNBS colitis in ΔdblGATA knockout and IL-5 transgenic mice.

Fig. 4

(A, B) Inflammation was reduced in ΔdblGATA knockouts (ko), but enhanced in IL-5 transgenic (tg) mice vs. wild-types (wt). Treatment of ΔdblGATA knockouts (ko) with 0.1 mg/kg OC-459 (OC) had no further effect on inflammation score and colon length. (C) Images show lack (ΔdblGATA ko) or high presence (IL-5 tg) of eosinophils in sections of inflamed colon of TNBS-induced colitis (n=7-12). Means±SD; *p<0.05; **p<0.01; one-way ANOVA. Controls (CTRL, no TNBS);