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. Author manuscript; available in PMC: 2016 Jun 3.
Published in final edited form as: Nature. 2016 Mar 16;531(7595):513–517. doi: 10.1038/nature16985

Extended Data Figure 7. cDCs confer anti-metastatic activity in the presence of a primary tumour.

Extended Data Figure 7

a, Experimental schema for evaluation of role of cDCs in lung metastasis in the presence of a primary tumour. b, Representative images of lungs from Zbtb46-DTR bone marrow chimaeras treated with PBS or DT after implantation of a primary subdermal tumour (1 × 105 B16F10 in matrigel) and i.v. metastases (1.5 × 105 B16ZsGreen). Metastases were assessed one week after i.v. injection. c, Quantification of total number of visible ZsGreen+ lung metastases in PBS- or DT-treated Zbtb46-DTR bone marrow chimaeras. n = 4–5 per group, representative of 2 experiments; *P < 0.05, unpaired t-test, horizontal bars are mean value.