Table 1. Parameter settings of virtual datasets.

Simulations	Number of causal CpGs	Location of causal CpGs	Correlation coefficient (r)	Values of βj
Scenario 1
1.1	0	-	0.2/0.4/0.6/0.8	-
1.2	1	1	0.2/0.4/0.6/0.8	0.5/0.6/0.7/0.8/0.9/1.0
1.3	2	1 and 2	0.2/0.4/0.6/0.8	0.1/0.2/0.3/0.4/0.5
Scenario 2
2.1	0	-	0.2/0.4/0.6/0.8	-
2.2	1	1	0.2/0.4/0.6/0.8	0.5/0.6/0.7/0.8/0.9/1.0
2.3	1	5	0.2/0.4/0.6/0.8	0.5/0.6/0.7/0.8/0.9/1.0
2.4	1	10	0.2/0.4/0.6/0.8	0.5/0.6/0.7/0.8/0.9/1.0
2.5	2	1 and 5	0.2/0.4/0.6/0.8	0.1/0.2/0.3/0.4/0.5
2.6	2	1 and 10	0.2/0.4/0.6/0.8	0.1/0.2/0.3/0.4/0.5
2.7	2	5 and 10	0.2/0.4/0.6/0.8	0.1/0.2/0.3/0.4/0.5