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. 2016 Jun 3;11(6):e0156363. doi: 10.1371/journal.pone.0156363

Fig 1. Antibody responses to L. infantum antigens post-vaccination.

Fig 1

The anti-PL IgG antibody responses were measured post-vaccination by ELISA (one day before infection). Mice were immunized intranasally with 3x15 μg promastigote lysate (PL) plus either wild-type CNF1 (PL + WT CNF1) or catalytically inactive CNF1 (PL + mCNF1). The controls represent infected but non-immunized animals. Serum samples were tested at a 1/100 dilution and evaluated using HRP-labeled anti-mouse IgG. The interquartile ranges as well as the 10–90% percentiles are presented for each group. ***: p<0.001. The results are representative of 2 independent experiments. n = 7.