Table 1. Comparison of the dynamic range of response between polarized SRM and SHG-based morphometry.
Efficacy study with ENA | Efficacy study with MMF | Efficacy study with EX76505 | Average (fold) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Veh | 15 mg/kg | 30 mg/kg | 60 mg/kg | Veh | 2 mg/kg | 20 mg/kg | Veh | 1 mg/kg | 3 mg/kg | 10 mg/kg | ||
SRM | 5.1 | 2.4 | 2.2 | 1.7 | 2.1 | 1.9 | 1.4 | 2.5 | 2.1 | 1.9 | 2.0 | 2.3 |
SHG | 4.8 | 2.9 | 2.3 | 2.7 | 4.6 | 4.3 | 3.7 | 6.0 | 5.5 | 5.6 | 3.0 | 4.1 |
Veh: vehicle; ENA: enalapril; MMF: mycophenolate mofetil; EX76505: CTGF neutralized antibody.