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. 2016 Jun 3;11(6):e0155990. doi: 10.1371/journal.pone.0155990

Fig 1. Synthesis of mvsFlt schematic.

Fig 1

mvsFlt bioconjugates were synthesized using a 3-step reaction in which HyA was reacted with EDC and EMCH to create a thiol reactive HyA-EMCH intermediate. sFlt was then treated with 2-iminothiolane and reacted with the HyA-EMCH intermediate for the synthesis of the final mvsFlt bioconjugate.