Table 2. Statistics (FC,T-test and FDR-adjusted p values) for the Ten Common Marker Genes in the Four Studied Datasets.
Gene symbol | GSE46907 (Monocyte) | GSE50772 (PBMC) | GSE61635 (Whole blood) | GSE49454 (Whole blood) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
FC | p-value | FC | p-value | FC | p-value | FC | p-value | |||||
T-Test | FDR(0.001) | T-Test | FDR(0.001) | T-Test | FDR(0.001) | T-Test | FDR(0.001) | |||||
IFI6 | 8.82 | 2.05E-03 | 1.17E-05 | 3.73 | 5.36E-11 | 3.67E-05 | 1.36 | 5.94E-28 | 1.34E-05 | 1.19 | 7.12E-17 | 2.86E-06 |
OAS1 | 3.38 | 2.85E-05 | 1.51E-07 | 2.51 | 2.80E-08 | 8.82E-05 | 1.3 | 8.94E-30 | 8.43E-06 | 1.24 | 5.33E-21 | 1.35E-06 |
OAS2 | 6.43 | 3.20E-04 | 1.81E-06 | 2.08 | 6.14E-09 | 7.11E-05 | 1.22 | 3.04E-29 | 1.02E-05 | 1.21 | 1.19E-15 | 3.16E-06 |
EIF2AK2 | 3.08 | 4.96E-04 | 3.61E-06 | 2.04 | 1.70E-10 | 4.34E-05 | 1.12 | 2.67E-29 | 9.94E-06 | 1.22 | 1.78E-11 | 5.27E-06 |
PLSCR1 | 2.36 | 5.45E-05 | 1.05E-06 | 2.02 | 3.36E-12 | 2.35E-05 | 1.22 | 9.46E-35 | 3.01E-06 | 1.19 | 2.58E-13 | 4.37E-06 |
IFI27 | 251.66 | 6.78E-02 | 1.78E-04 | 74.06 | 1.14E-07 | 1.04E-04 | 1.4 | 6.06E-16 | 1.25E-04 | 1.87 | 3.55E-18 | 2.41E-06 |
IFI44L | 11.7 | 1.07E-03 | 6.62E-06 | 5.55 | 4.72E-10 | 5.04E-05 | 1.35 | 5.55E-22 | 4.43E-05 | 1.52 | 1.24E-24 | 4.52E-07 |
STAT1 | 2.68 | 4.38E-03 | 2.32E-05 | 1.63 | 5.11E-09 | 6.82E-05 | 1.07 | 8.85E-17 | 1.10E-04 | 1.1 | 6.93E-15 | 3.31E-06 |
RNASE2 | 3.8 | 1.87E-02 | 7.21E-05 | 3 | 1.53E-11 | 2.98E-05 | 1.06 | 2.67E-06 | 4.35E-04 | 1.17 | 4.63E-10 | 7.83E-06 |
GSTO1 | 1.02 | 0.889 | 9.31E-04 | 1.65 | 3.10E-15 | 5.87E-06 | 1.01 | 5.76E-04 | 5.81E-04 | 1.04 | 6.52E-06 | 3.01E-05 |
Note: FC: fold-change; FDR: false discovery rate. Values in bold mean the corresponding genes were selected as significant from the corresponding datasets/samples under the corresponding methods. IFI6: interferon, alpha-inducible protein 6; OAS1: 2'-5'-oligoadenylate synthetase 1; OAS2: 2'-5'-oligoadenylate synthetase 2; EIF2AK2: eukaryotic translation initiation factor 2-alpha kinase 2; PLSCR1: phospholipid scramblase 1; IFI27:interferon, alpha-inducible protein 27; IFI44L:interferon-induced protein 44-like; STAT1:signal transducer and activator of transcription 1; GSTO1:glutathione S-transferase omega 1; RNASE2:ribonuclease, RNase A family, 2.