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. 2016 Jun 3;11(6):e0155856. doi: 10.1371/journal.pone.0155856

Table 1. Definitions of clinical TNM according AJCC 2010 [21].

Primary tumor (pT)
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
Clinically inapparent tumor neither palpable nor visible by imaging (T1)
T1a Tumor incidental histologic finding in ≤ 5% of tissue resected
T1b Tumor incidental histologic finding in > 5% of tissue resected
T1c Tumor identified by needle biopsy (e.g. because of elevated PSA)
Tumor confined within prostate (T2)
T2a Tumor involves one-half of one lobe or less
T2b Tumor involves more than one-half of one lobe but not both lobes
T2c Tumor involves both lobes
Tumor extends through the prostate capsule (T3)
T3a Extracapsular extension (unilateral or bilateral)
T3b Tumor invades seminal vesicle(s)
T4 Tumor is fixed or invades adjacent structures other than seminal vesicles such as external sphincter, rectum, bladder, levator muscles, and/or pelvic wall
Regional lymph nodes (pN)
NX Regional lymph nodes were not assessed
N0 No regional lymph node metastasis
N1 Metastasis in regional lymph node(s)
Distant metastasis (pM)
M0 No distant metastasis
M1 Distant metastasis
M1a Non-regional lymph node(s)
M1b Bone(s)
M1c Other site(s) with or without bone disease