Table 1.
Demographics and neuropsychological assessment
| Case | 1 | 5 | 7 | 10 | 12 | 14 | 17 | 19 | 6 | 13 | 15 | 20 | 21 | 22 | 16 | 4 | 9 | 11 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age | 76 | 70 | 61 | 64 | 64 | 48 | 58 | 69 | 52 | 79 | 71 | 78 | 72 | 63 | 71 | 57 | 64 | 62 | |
| Sex | M | F | M | F | M | F | F | F | F | F | M | M | F | F | M | F | M | F | |
| Education level (years) | 14 | 12 | 17 | 12 | 8 | 12 | 10 | 7 | 17 | 8 | 15 | 17 | 12 | 15 | 15 | 15 | 17 | 15 | |
| PPA subtype | SV | SV | SV | SV | SV | SV | SV | SV | NFV | NFV | NFV | NFV | NFV | NFV | LV | LV | LV | LV | |
| Disease duration (years) | 6 | 1,5 | 3 | 3 | 3 | 6 | 2 | 5 | 2 | 5 | 1,5 | 2,5 | 2,5 | 5 | 1 | 0,5 | 3 | 1,5 | |
| FDG PET | + | + | + | + | + | + | + | + | - | + | + | + | - | + | - | + | + | + | |
| PIB PET SUVRcomp | 1,15 | - | - | - | - | - | - | - | 1,2 | - | - | - | - | 1.16 | - | 1,81 | 2,24 | - | |
| CSF Aβ42 (pg/ml) | - | 1330 | - | - | - | - | - | 733 | - | 1028 | - | 816 | 1060 | 865 | - | 664 | - | 516 | |
| CSF total tau (pg/ml) | - | 269 | - | - | - | - | - | 262 | - | 312 | - | 195 | 424 | 183 | - | 183 | - | >1200 | |
| BNT (/60) | 34 | 22 | 7 | 10 | 20 | 12 | 35 | 16 | 58 | 48 | 55 | 48 | 30 | 41 | 53 | 56 | 41 | 53 | |
| PALPA comprehension | |||||||||||||||||||
| Auditory WP matching (/40) | 38 | 36 | 31 | 29 | 31 | 27 | 40 | 30 | 40 | 40 | 37 | 39 | 36 | 38 | 40 | 40 | 40 | 40 | |
| Verbal assoc.-sem. (/30) | 27 | 17 | 18 | 22 | 14 | 24 | 27 | 21 | 28 | 22 | 28 | 23 | 19 | 24 | 28 | 28 | 23 | 27 | |
| AAT comprehension | |||||||||||||||||||
| Auditory word (/30) | 19 | 15 | 11 | 19 | 19 | 11 | 21 | 14 | 30 | 27 | 27 | 24 | 20 | 21 | 28 | 30 | 29 | 25 | |
| Auditory sentence (/30) | 26 | 20 | 25 | 19 | 20 | 25 | 21 | 24 | 30 | 24 | 25 | 12 | 23 | 25 | 30 | 30 | 27 | 25 | |
| Written word (/30) | 20 | 18 | 13 | 11 | 13 | 19 | 24 | 14 | 30 | 30 | 25 | 23 | 21 | 28 | 30 | 30 | 30 | 26 | |
| Written sentence (/30) | 25 | 21 | 24 | 23 | 22 | 27 | 27 | 30 | 30 | 24 | 25 | 18 | 21 | 30 | 30 | 30 | 28 | 30 | |
| PALPA repetition | |||||||||||||||||||
| Single word (/80) | 72 | 78 | 78 | 79 | 71 | 79 | 76 | 78 | 76 | 74 | 74 | 74 | 69 | 80 | 80 | 80 | 77 | 80 | |
| Pseudoword (/80) | 55 | 71 | 74 | 65 | 56 | 80 | 72 | 77 | 55 | 59 | 40 | 54 | 30 | 79 | 63 | 74 | 69 | 79 | |
| AAT repetition | |||||||||||||||||||
| Total score (/150) | 147 | 147 | 141 | 150 | 143 | 150 | 148 | 146 | 134 | 125 | 123 | 144 | 102 | 148 | 140 | 147 | 145 | 150 | |
| Phonemes (/30) | 30 | 28 | 29 | 30 | 28 | 30 | 30 | 30 | 28 | 29 | 30 | 29 | 26 | 30 | 27 | 30 | 28 | 30 | |
| Single words (/30) | 27 | 29 | 29 | 30 | 27 | 30 | 30 | 28 | 26 | 24 | 21 | 30 | 28 | 30 | 30 | 30 | 29 | 30 | |
| Cognate words (/30) | 30 | 30 | 30 | 30 | 30 | 30 | 30 | 29 | 28 | 22 | 29 | 28 | 24 | 30 | 29 | 30 | 30 | 30 | |
| Object decision | |||||||||||||||||||
| Easy B (/32) | 23 | 18 | 20 | 21 | 26 | 26 | 31 | 23 | 31 | 30 | 31 | 26 | 18 | 22 | 31 | 29 | 31 | 31 | |
| Hard A (/32) | 20 | 20 | 18 | 18 | 18 | 17 | 27 | 17 | 26 | 25 | 26 | 29 | 21 | 28 | 26 | 25 | 25 | 24 | |
| PPT Pictures (/52) | 37 | 39 | 40 | 35 | 40 | 46 | 50 | 43 | 52 | 51 | 50 | 47 | 46 | 48 | 50 | 51 | 51 | 52 | |
| Digit Span forward | 6 | 3 | - | 6 | 6 | 6 | 5 | 5 | 6 | 3 | 4 | 6 | 2 | 4 | - | 4 | 7 | 5 | |
| CPM (/36) | 29 | 24 | 36 | 31 | 29 | 35 | 36 | 34 | 31 | 24 | 24 | 30 | 12 | 32 | 33 | 35 | 33 | 31 | |
FDG PET = 18F-fluorodeoxyglucose positron emission tomography; PIB PET SUVRcomp = Pittsburgh compound-B PET standardized uptake value ratio in the composite cortical volume of interest; WP = word-picture; PPT = Pyramids and Palm Trees test.
– = Test was not performed.
Bold indicates >2 SD below the mean according to published norms.