Table 1.
Groups | Day
|
|||
---|---|---|---|---|
0, 14, and 28 | 49, 56, and 63 | 77 | 119 | |
Carrier–vaccine | Carriera | Vaccineb | TC-1 | Sacrifice and immunoassay |
PBS–vacci ne | PBSa | Vaccineb | TC-1 | |
PBS–PBS | PBSa | PBSb | TC-1 | |
PBS–carrier | PBSa | Carrierb | TC-1 |
Notes:
The carrier was immunized sc to induce the anti-HBcAg antibody, and PBS was administered as a control.
HBcAg-E749–57 was immunized sc to induce E749–57-specific antitumor immunity, and carrier and PBS were administered as controls.
Abbreviations: sc, subcutaneous; HBcAg, hepatitis B core antigen; PBS, phosphate-buffered saline.