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. 2016 Jan 29;48(1):e206. doi: 10.1038/emm.2015.102

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Copyright © 2016 KSBMB.

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Selective effects of CHMP5 knockdown on TCR-induced genes. (a–c) RNA was extracted from Ctrl and CHMP5^KD Jurkat cells treated with anti-CD3/anti-CD28 for 1, 3, 9, 12 and 24 h, followed by an analysis of the expression of T-cell immunity–related genes (a), intracellular signaling–related genes (b), and kinase-related genes (c) in Ctrl and CHMP5^KD Jurkat cells (CHMP5^KD versus Ctrl Jurkat cells). Lane 1, Unstimulated cells; Lane 2, TCR stimulation for 1 h; Lane 3, TCR stimulation for 3 h; Lane 4, TCR stimulation for 9 h; Lane 5, TCR stimulation for 12 h; Lane 6, TCR stimulation for 24 h.