Table S1.
Factors associated with DFS in univariate analysis (n=170)
| Variables | No of patients | DFS
|
||
|---|---|---|---|---|
| Five-year rate (%) | HR | P-value | ||
| Age at diagnosis (years) | ||||
| <35 | 34 | 73.4 | 1 | |
| 35–45 | 82 | 65.3 | 1.26 | 0.57 |
| ≥45 | 54 | 57.6 | 2.00 | 0.09 |
| Parity | ||||
| <2 | 76 | 68.9 | 1 | |
| ≥2 | 85 | 62.3 | 1.34 | 0.31 |
| Unknown | 9 | |||
| Histology | ||||
| Squamous | 145 | 64.1 | 1 | |
| Adenocarcinoma and adenosquamous | 25 | 70.4 | 0.95 | 0.89 |
| Grade | ||||
| 1 | 18 | 76.2 | 1 | |
| 2 | 90 | 63.7 | 1.43 | 0.51 |
| 3 | 62 | 64.8 | 1.89 | 0.24 |
| Tumor size | ||||
| <4 cm | 122 | 66.0 | 1 | |
| ≥4 cm | 48 | 62.5 | 1.31 | 0.36 |
| Number of positive lymph nodes | ||||
| <3 | 107 | 73.7 | 1 | |
| ≥3 | 63 | 49.6 | 1.85 | 0.02 |
| Bilaterality of lymph node metastasis | ||||
| Unilateral | 99 | 72.0 | 1 | |
| Bilateral | 71 | 54.4 | 1.47 | 0.16 |
| Common iliac lymph node metastasis | ||||
| No | 145 | 70.3 | 1 | |
| Yes | 25 | 35.6 | 3.19 | <0.001 |
| FIGO stage | ||||
| IB1 | 76 | 74.4 | 1 | |
| IB2 | 29 | 70.3 | 1.29 | 0.55 |
| IIA | 49 | 53.6 | 2.07 | 0.02 |
| IIB | 16 | 57.9 | 1.69 | 0.24 |
| Lymph vascular space invasion | ||||
| No | 124 | 74.4 | 1 | |
| Yes | 46 | 55.1 | 1.71 | 0.055 |
| Vaginal margin | ||||
| Negative | 161 | 72.9 | 1 | |
| Positive | 9 | 27.8 | 1.90 | 0.17 |
| Parametrial infiltration | ||||
| No | 152 | 73.8 | 1 | |
| Yes | 18 | 37.0 | 2.76 | 0.002 |
| Corpus invasion | ||||
| No | 156 | 73.4 | 1 | |
| Yes | 14 | 55.0 | 1.39 | 0.45 |
| Deep stromal invasion | ||||
| No | 72 | 70.3 | 1 | |
| Yes | 98 | 60.4 | 1.61 | 0.10 |
Abbreviations: DFS, disease-free survival; HR, hazards ratio; FIGO, Federation of Gynaecology and Obstetrics.