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. Author manuscript; available in PMC: 2016 Jun 3.
Published in final edited form as: Nat Commun. 2012;3:1279. doi: 10.1038/ncomms2229

Figure 4. Teratoma assay of mouse iPSCs generated using different POU factors.

Figure 4

Hematoxylin and eosin-stained sections of teratomas formed 4 weeks after subcutaneously injecting nude mice with mouse iPSCs generated using the different POU factors. Teratomas contain all three embryonic germ layers: endoderm (respiratory epithelium (e)), mesoderm (cartilage (c), skeletal muscle (m), adipose tissue (f)) and ectoderm (neural epithelium with rosettes (n), pigmented melanocytes (p)). Scale bars, 100 µm.