Table 1.

Chronicle of major neurotoxicology events in China from 3000 BCE to 2014 AD.

Date	Events
3000 BCE	Bronze use began in China (Lee et al. 2008)
200 CE	Zhongjing Zhang described the symptoms and treatment of mushroom-induced neurotoxicity in Synopsis of Prescriptions of the Golden Chamber (Zhang 2012)
610 CE	Yuanfang Chao further described mushroom-induced neurotoxicity in General Treatise on the Cause and Symptoms of Diseases (Chao 2009)
1593 CE	Shizhen Li described the toxicity of lead, use of herbal medicines against mushroom-induced toxicities, and neurotoxicity of tetrodotoxin from globefish in Compendium of Materia Medic (Li 2005)
1965 CE	Chelating therapy for lead intoxications was introduced into China (Wang et al. 1965)
1979 CE	Environmental Protection Law approved for trial implementation (National People’s Congress 1979)
1982 CE	First edition of Ambient Air Quality Standard issued (SEPA 1982); Marine Environment Protection Law adopted (National People’s Congress 1982)
1984 CE	Law on Prevention and Control of Water Pollution adopted (National People’s Congress 1984)
1985 CE	First edition of Standards for Drinking Water Quality released (MOH 1985)
1986 CE	WHO Neurobehavioral Core Test Battery (NCTB) introduced into China (Chen et al. 1999)
1987 CE	First edition of Law on the Prevention and Control of Atmospheric Pollution enacted (National People’s Congress 1987)
1988 CE	Computer-based Chinese Version of the Neurobehavioral Evaluation System (NES-C1) was formed (Chen et al. 1999)
1989 CE	Environmental Protection Law amended and formal one adopted (National People’s Congress 1989); six cases of chronic manganese intoxication in workers at a ferromanganese factory reported (Huang et al. 1989)
1995 CE	Law on Prevention and Control of Environmental Pollution by Solid Waste adopted (National People’s Congress 1995b); second edition of Law on the Prevention and Control of Atmospheric Pollution adopted (National People’s Congress 1995a)
1996 CE	Second edition of Ambient Air Quality Standard released (SEPA 1996); second edition of Law on Prevention and Control of Water Pollution adopted (National People’s Congress 1996)
1999 CE	Second edition of Marine Environment Protection Law adopted (National People’s Congress 1999)
2000 CE	Third edition of Law on the Prevention and Control of Atmospheric Pollution adopted (National People’s Congress 2000); use of leaded gasoline banned (He et al. 2009)
2002 CE	Indoor Air Quality Standard of China released (SEPA 2002)
2004 CE	Second edition of Law on Prevention and Control of Environmental Pollution by Solid Waste adopted (National People’s Congress 2004)
2006 CE	Second edition of Standards for Drinking Water Quality released (MOH 2006b); the “Trial Implementation Guide to The Classification and Treatment Principles for Child-Related High Blood Lead Levels and Lead Poisoning Cases” was released (MOH 2006a)
2008 CE	China upgraded State Environmental Protection Administration (SEPA) to be Ministry of Environmental Protection (MEP) (Qiu and Li 2008); third edition of Law on Prevention and Control of Water Pollution adopted (National People’s Congress 2008)
2010 CE	The Chinese Neurotoxicology Association (CNA) established (Chinese Society of Toxicology 2010)
2011 CE	Xi’an International Neurotoxicology Conference (XINC) held (Fox et al. 2012; Zheng 2012)
2012 CE	Third edition of Ambient Air Quality Standard released (MEP 2012)
2013 CE	Third edition of Law on Prevention and Control of Environmental Pollution by Solid Waste adopted (National People’s Congress 2013a); third edition of Marine Environment Protection Law adopted (National People’s Congress 2013b)
2014 CE	Second edition of Environmental Protection Law adopted (National People’s Congress 2014)