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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Pharm Res. 2016 Mar 14;33(7):1649–1656. doi: 10.1007/s11095-016-1904-6

Figure 6. TAF TFPD Prototypes.

Figure 6

(A) Device parameters and predicted release rates for TAF TFPD prototype devices. Each group consists of n=3 devices and measurements represent average values +/− 1 standard deviation. (B) Cumulative release profiles for prototype device groups. Prototype devices are loaded with a 1:1 TAF:PEG300 (w/w) formulation. Release profile is linear (solid data points) until device nears depletion (outlined data points). Linear regression determines average release rate for each prototype group (mg/day). (C) Purity of TAF remaining in device reservoir after incubation under physiological conditions (PBS pH 7.4, 37°C).