Clinical event rates are the primary composite outcome consisting of all-cause death, myocardial infarction, or unstable angina hospitalization. The top 2 panels compare positive test rates and event rates by sex in patients undergoing CTA vs. stress testing. In women event rates are similar in the 2 arms, but test positivity rates are higher in the stress test arm. In men event rates are also similar in the 2 arms, but test positivity rates are higher in the CTA arm. The bottom 2 panels compare event rates by positive and negative test results for each sex and by test type. Within women, the event rate with a negative CTA was similar to that with a negative stress test, but the event rate with a positive CTA was higher than that with a positive stress test. Within men, the event rate with a negative CTA was similar to that with a negative stress test, as was the event rate with a positive CTA and a positive stress test.