Table 3.
Positive Test Rate, No. of Positive Tests/Sample Size (%) | CTA versus Stress Test Unadjusted* | CTA versus Stress Test Adjusted† | ||||
---|---|---|---|---|---|---|
Model/Comparison | CTA | Stress Test | Odds Ratio (95% CI) | P-value | Odds Ratio (95% CI) | P-value |
Interaction between randomized arm and sex | --- | < 0.001 | --- | < 0.001 | ||
CTA versus stress test in women | 184/2332 (7.89%) | 274/2388 (11.47%) | 0.66 (0.54 - 0.80) | < 0.001 | 0.67 (0.55 - 0.82) | < 0.001 |
CTA versus stress test in men | 350/2168 (16.14%) | 290/2078 (13.96%) | 1.19 (1.00 - 1.41) | 0.047 | 1.23 (1.04 - 1.47) | 0.019 |
Unadjusted models contained sex, randomized testing arm, and interaction term.
Adjusted for age, race, body mass index, coronary artery disease (CAD) equivalent, Framingham risk score (12), ASCVD (13), Diamond and Forrester (14), hypertension, dyslipidemia, diabetes, family history of premature CAD, sedentary lifestyle, smoking, typicality of chest pain, and physician's estimation of likelihood of significant CAD.
CTA = computed tomographic angiography; NIT = noninvasive test.