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. Author manuscript; available in PMC: 2017 Jun 7.
Published in final edited form as: J Am Coll Cardiol. 2016 Apr 4;67(22):2607–2616. doi: 10.1016/j.jacc.2016.03.523

Table 3.

Association Between Noninvasive Test Type and Positive Test Results in Women and in Men

Positive Test Rate, No. of Positive Tests/Sample Size (%) CTA versus Stress Test Unadjusted* CTA versus Stress Test Adjusted

Model/Comparison CTA Stress Test Odds Ratio (95% CI) P-value Odds Ratio (95% CI) P-value
Interaction between randomized arm and sex --- < 0.001 --- < 0.001
    CTA versus stress test in women 184/2332 (7.89%) 274/2388 (11.47%) 0.66 (0.54 - 0.80) < 0.001 0.67 (0.55 - 0.82) < 0.001
    CTA versus stress test in men 350/2168 (16.14%) 290/2078 (13.96%) 1.19 (1.00 - 1.41) 0.047 1.23 (1.04 - 1.47) 0.019
*

Unadjusted models contained sex, randomized testing arm, and interaction term.

Adjusted for age, race, body mass index, coronary artery disease (CAD) equivalent, Framingham risk score (12), ASCVD (13), Diamond and Forrester (14), hypertension, dyslipidemia, diabetes, family history of premature CAD, sedentary lifestyle, smoking, typicality of chest pain, and physician's estimation of likelihood of significant CAD.

CTA = computed tomographic angiography; NIT = noninvasive test.