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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Stem Cells. 2016 Mar 15;34(6):1626–1636. doi: 10.1002/stem.2307

Figure 7. BVES modulates stem cell regenerative responses and Wnt signaling after radiation.

Figure 7

Proximal small intestine was harvested from WT or Bves−/− mice after 12 Gy WBR. qRT-PCR analysis revealed increases in mRNA expression of (A) +4 stem cell markers Bmi1 and TERT and (B) CBC stem cell markers Lgr5 and Ascl2 in Bves−/− proximal SI compared to WT. Expression of (C) Wnt ligands, (D) Wnt receptors, and (E) Wnt targets was significantly elevated in the Bves−/− proximal SI compared to WT. (*P<0.05, **P<0.01, n=12)