Table 4.
Neonatal Characteristics of FMH-Impacted Pregnancies Compared to Controls
Number (%) or Mean ± SD | p value | |||
---|---|---|---|---|
Cases (n = 23) | Controls (n = 46) | |||
Neonatal course | NICU admission | 23 (100) | 11 (12) | <0.001* |
First hemoglobin (mg/dL) | 7.2 ± 2.8 | 16.8 ± 2.4 | <0.001* | |
First reticulocyte count (%) | 9.2 ± 5.6 | 7.4 ± 3.3 | <0.001* | |
Highest total bilirubin (mg/dL) | 10.6 ± 5.3 | 10.5 ± 2.5 | 0.913 | |
Intubation and mechanical ventilation | 9 (39) | 3 (3.3) | <0.001* | |
Central line placed | 13 (57) | 2 (2.2) | <0.001* | |
Blood (packed red cell) transfusion | 17 (74) | 2(2.2) | <0.001* | |
Platelet transfusion | 2 (8.7) | 1 (1.1) | 0.11 | |
Hypotension | 8 (35) | 4 (4.4) | <0.001* | |
Persistence of the fetal circulation | 3 (13) | 0 (0) | 0.002* | |
Hypoxic-ischemic encephalopathy | 2 (8.7) | 0 (0) | <0.001* | |
Post-NICU | Home | 19 (83) | 91 (99) | 0.006* |
Transitional or long-term care facility | 1 (4.3) | 0 (0) | 0.12 | |
Deceased1 | 3 (13) | 1 (1.1) | 0.03* |
Significant at p<0.05
Causes of death for cases were cerebral herniation, pulmonary hypertension, and cardiopulmonary arrest. Cause of death for the control was inborn error of metabolism.