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. 2016 Feb 26;11:316–321. doi: 10.1016/j.nicl.2016.02.016

Fig. 1.

Fig. 1

The pseudoprogression and glioblastoma recurrence findings on MRI. Representative MRI examples of the pseudoprogression (A–E) and glioblastoma relapse (F–J): (A) + (G) show T1WI, (B) + (H) show T1WI with gadolinium, (C) + (I) show T2WI, (D) + (J) show the ADC maps with marked VOI and corresponding ADCmean values, and (E) + (F) show the proton MR spectroscopy maps focused on tCho/tNAA concentration ratio with marked VOI, corresponding values and spectra. The MR spectra illustrate concentrations of the main metabolites within the selected voxel. The color scale for the tCho/tNAA ratio corresponds to the color map shown for the MRSI grids overlaid on top of the MR images. The signal-to-noise ratio of the presented MR spectra is 4.98 in pseudoprogression and 4.86 in glioblastoma recurrence as well as the error of tCho/tNAA concentration 7% and 4%, respectively.