Table 2.
Calculated cut-offs for the diagnosis of a tumor recurrence with related sensitivity and specificity for the most important concentration ratios of the metabolites measured by MRS and for ADCmean.
| Metabolite | AUC (95% CI) | p | Cut-off for recurrence | Sensitivity | Specificity |
|---|---|---|---|---|---|
| tCho/tNAA | 0.993 (0.978; 1.000) | < 0.001 | ≥ 1.3 | 100.0 | 94.7 |
| tCho/tCr | 0.691 (0.539; 0.843) | 0.013 | ≥ 0.7 | 74.6 | 63.2 |
| tNAA/tCr | 0.949 (0.873; 1.000) | < 0.001 | ≤ 0.7 | 96.6 | 94.7 |
| Lac + Lip 1.3/tCr | 0.714 (0.559; 0.868) | 0.003 | ≥ 1.6 | 76.3 | 68.4 |
| Lac + Lip 0.9–1.3/tCr | 0.723 (0.568; 0.879) | 0.004 | ≥ 2.0 | 78.0 | 68.4 |
| ADCmean [10− 6 mm2/s] | 0.998 (0.993; 1.000) | < 0.001 | ≤ 1313 | 98.3 | 100.0 |